N,N-Carbonyl Diimidazole Cdi is an organic compound with the chemical formula C7H6N4O. It is a colorless solid that is soluble in many organic solvents such as dichloromethane, acetonitrile, and ethanol. CDI is a coupling reagent that is widely used in peptide synthesis reactions to activate the carboxyl group of amino acids, enabling them to react with the amino group of other amino acids to form peptide bonds. It can also be used in the preparation of other amide-based compounds, such as ureas, thioureas, and lactams. N,N-Carbonyl Diimidazole Cdi is a valuable intermediate in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. It has advantages over other coupling reagents, such as DCC (dicyclohexylcarbodiimide), due to its higher solubility and reactivity, and its ability to react under mild conditions.
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